The luminal Ca2+ chelator, TPEN, inhibits NAADP-induced Ca2+ release
نویسندگان
چکیده
منابع مشابه
The luminal Ca2+ chelator, TPEN, inhibits NAADP-induced Ca2+ release
The regulation of Ca(2+) release by luminal Ca(2+) has been well studied for the ryanodine and IP(3) receptors but has been less clear for the NAADP-regulated channel. In view of conflicting reports, we have re-examined the issue by manipulating luminal Ca(2+) with the membrane-permeant, low affinity Ca(2+) buffer, TPEN, and monitoring NAADP-induced Ca(2+) release in sea urchin egg homogenate. ...
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ژورنال
عنوان ژورنال: Cell Calcium
سال: 2012
ISSN: 0143-4160
DOI: 10.1016/j.ceca.2012.09.001